Oncolytic Bluetongue Viruses: Promise, Progress, and Perspectives

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Oncolytic Bluetongue Viruses: Promise, Progress, and Perspectives

Humans are sero-negative toward bluetongue viruses (BTVs) since BTVs do not infect normal human cells. Infection and selective degradation of several human cancer cell lines but not normal ones by five US BTV serotypes have been investigated. We determined the susceptibilities of many normal and human cancer cells to BTV infections and made comparative kinetic analyses of their cytopathic effec...

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ژورنال

عنوان ژورنال: Frontiers in Microbiology

سال: 2011

ISSN: 1664-302X

DOI: 10.3389/fmicb.2011.00046